CARMO is a web-based platform providing comprehensive annotations for multi-omics data, including transcriptomic data sets, epi-genomic modification sites, SNPs from genome re-sequencing, and the large gene lists derived from these omics studies. Well-organized results, as well as multiple tools for interactive visualization, are available through a user-friendly web interface.

The power of CARMO lies in the comprehensive collection and integration of information from both multi-omics data and diverse functional evidence of rice, which was further curated into gene sets and higher level gene modules. In this way, the high-throughput data can easily be compared across studies and platforms, and notably, integration of multiple types of evidence provides biological interpretation from the level of modules with high confidence. Examples in the manuscripts demonstrated that CARMO not only reproduced reported evidence, but also proposed novel functional insights for further experimental exploration.

CARMO framework for data integration and web-based services

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